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Beilstein J. Org. Chem. 2022, 18, 1040–1046, doi:10.3762/bjoc.18.105
Graphical Abstract
Scheme 1: Generation of N-acyliminium ion: previous and present works.
Scheme 2: Electrochemical amidomethylation of indoles 4 in DMA.
Scheme 3: Electrochemical amidomethylation of 3-methyl-1H-indole (7) in DMA.
Scheme 4: Electrochemical amidomethylation of N-methyl-1H-indole (4a) in DMF.
Scheme 5: Probable reaction pathway of the electrochemical amidomethylation.